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SGC Experimental Information Sheet |
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The data presented in this document represent preliminary experimental observations
for a de-prioritized SGC target.
We provide this information as a general service to the research community at large,
with the caveat that the data may not have been subjected to rigorous review.
Queries regarding this document or access to reagents may be addressed to
alex.hodgson@utoronto.ca
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| Target ID |
ESRRB |
| Description |
estrogen-related receptor beta |
| Nucleotide accession |
NM_004452 |
| Protein accession |
NP_004443 |
Expression constructs: |
| Construct #1 |
| Construct DNA sequence |
CCTGCTAAAAAGCCATTGACCAAGATTGTCTCATACCTACTGGTGGCTGAGCCGGACAAGCTCTATGCCATGCCTCCCCC
TGGTATGCCTGAGGGGGACATCAAGGCCCTGACCACTCTCTGTGACCTGGCAGACCGAGAGCTTGTGGTCATCATTGGCT
GGGCCAAGCACATCCCAGGCTTCTCAAGCCTCTCCCTGGGGGACCAGATGAGCCTGCTGCAGAGTGCCTGGATGGAAATC
CTCATCCTGGGCATCGTGTACCGCTCGCTGCCCTACGACGACAAGCTGGTGTACGCTGAGGACTACATCATGGATGAGGA
GCACTCCCGCCTCGCGGGGCTGCTGGAGCTCTACCGGGCCATCCTGCAGCTGGTACGCAGGTACAAGAAGCTCAAGGTGG
AGAAGGAGGAGTTTGTGACGCTCAAGGCCCTGGCCCTCGCCAACTCCGATTCCATGTACATCGAGGATCTAGAGGCTGTC
CAGAAGCTGCAGGACCTGCTGCACGAGGCACTGCAGGACTACGAGCTGAGCCAGCGCCATGAGGAGCCCTGGAGGACGGG
CAAGCTGCTGCTGACACTGCCGCTGCTGCGGCAGACGGCCGCCAAGGCCGTGCAGCACTTCTATAGCGTCAAACTGCAGG
GCAAAGTGCCCATGCACAAACTCTTCCTGGAGATGCTGGAGGCCAAGGCC
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| Construct AA sequence |
PAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEI
LILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAV
QKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKA
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| Vector |
p28a-thrombin-lic |