About SGC

The SGC is a not-for-profit organization that aims to determine the three dimensional structures of proteins of medical relevance, and place them in the public domain without restriction. The SGC operates out of the Universities of Oxford and Toronto and Karolinska Institutet, Stockholm, and works on structures of proteins from its funder-created Target List of ~2,000 proteins, which comprises human proteins associated with diseases such as cancer, diabetes, inflammation, and genetic and epigenetic diseases, as well as proteins from human parasites such as those that cause malaria. The SGC released its 450^th structure in June 2007.  Over the next four years, the SGC will generate and release the structures of another 600 proteins from the Target List, including several human integral membrane proteins.

Research at the SGC is focused on understanding the structural relationships between proteins and the ligands that they bind, and our scientists publish extensively and operate in a highly collaborative mode.